Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Mar 2013
Trends in utilization and outcomes of bariatric surgery in obese people with and without type 2 diabetes in Spain (2001-2010).
Bariatric surgery is associated with a significant improvement in glucose control and even diabetes remission. There are no studies investigating national trends in the use of bariatric surgery in people with type 2 diabetes. We examine trends in the use of bariatric surgery in patients with and without type 2 diabetes between 2001 and 2010 in Spain. ⋯ The proportion of subjects with type 2 diabetes among bariatric surgery patient has increased over time, in part due to an increase in the use of laparoscopic techniques.
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Diabetes Res. Clin. Pract. · Mar 2013
Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance.
To detect plasma secreted frizzled-related protein (SFRP) 5 levels in Chinese healthy, obese and type 2 diabetes mellitus (T2DM) subjects and to investigate the relationships between plasma SFRP5 levels and body fat parameters, insulin resistance, glucolipid metabolism and inflammation. ⋯ Plasma levels of SFRP5 were decreased in Chinese obese and T2DM subjects. SFRP5 was an independent factor affecting glucolipid metabolism, inflammation and IR. It may play an important role in the pathogenesis of obesity and T2DM.