Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Aug 2019
Interactive effects of prepregnancy overweight and gestational diabetes on macrosomia and large for gestational age: A population-based prospective cohort in Tianjin, China.
Obesity increases risk of gestational diabetes mellitus (GDM) and GDM increases risk of macrosomia but their inter-relations for increased risk of macrosomia remain uncertain. We aimed to examine associations between prepregnancy overweight and macrosomia, and synergistic effects between prepregnancy overweight and GDM on macrosomia. ⋯ Prepregnancy overweight increased the risks of macrosomia and LGA independently and synergistically with GDM.