Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Jun 1999
Comparative StudyEvaluation of a real-time blood glucose monitor in children with diabetic ketoacidosis.
Use of a real-time bedside glucose monitor was analyzed during the course of management of diabetic ketoacidosis (DKA) in children. Simultaneous determinations of blood glucose were obtained, using three methods: bedside glucose meter (One Touch II), laboratory glucose analyzer (YSI 2300 STAT), and a real-time bedside glucose monitor (VIA 1-01G Blood Chemistry monitor). Study patients included seventeen patients < 18 years of age admitted to a Pediatric Intensive Care Unit, with blood samples obtained during treatment of DKA by continuous insulin infusion. ⋯ YSI 2300 STAT, respectively (all P-values < 0.0001). This real-time bedside glucose monitor is accurate at glucose values < 13.8 mmol/l, and reliable for rapid, repetitive analyses. Results indicate that blood glucose values obtained using this real-time monitor are comparable to those using standard methods of measurement, and that this device is clinically applicable for use in management of children with DKA.
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Infection with rare organisms or at unusual sites occur more frequently in people with diabetes. If not recognised and treated promptly, morbidity and mortality are high in such cases. Here we report cases of necrotising fascitis, malignant otitis externa, Fournier's gangrene and psoas abscess occurring in diabetics that needed intensive treatment with antibiotics, surgical debridement and insulin. Literature reviews suggest that cellular defence mechanisms may be impaired in people with diabetes.
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Diabetes Res. Clin. Pract. · Jan 1998
Does peripheral neuropathy invariably accompany nephropathy in type 1 diabetes mellitus?
In patients with Type 1 diabetes mellitus complicated by diabetic nephropathy and retinopathy, it is usually believed that significant neuropathy is almost universal, but few studies have directly addressed this. This study assessed neuropathy in 91 such subjects, using vibration perception thresholds (VPT) and the neuropathy disability score (NDS). ⋯ These factors together accounted for only 12 and 31% of the total variance in VPT z score and NDS, respectively. In conclusion, the study has shown that a significant proportion of patients with diabetic nephropathy are free of neuropathy, but the full explanation for their protection from neuropathy is unclear.
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Diabetes Res. Clin. Pract. · Sep 1996
Acid-base and electrolyte disturbances in patients with diabetic ketoacidosis.
We undertook the present study to examine the acid-base and electrolyte disturbances in relation to hydration status in patients with diabetic ketoacidosis (DKA). A total of 40 insulin-dependent diabetes mellitus patients (22 male, 18 female), aged 18-61 years with DKA admitted to our hospital during the last 2 years, were studied. The duration of diabetes averaged 9 +/- 2 years. ⋯ However, contradictorily, the severely dehydrated patients who experienced recurrent episodes of vomiting developed DKA with a concurrent metabolic alkalosis. Finally, patients with pneumonia or gram-negative septicemia exhibited DKA combined with a primary respiratory alkalosis. We conclude that patients with DKA commonly develop mixed acid-base disorders, which are partly dependent on patients' hydration status.
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Diabetes Res. Clin. Pract. · Dec 1995
IDF Member Associations' activities presented in the 15th IDF Congress Exhibition.
IDF Member Associations' activities were presented in the 15th IDF Congress Exhibition held at Port Island, Kobe, Japan from November 7 to November 11, 1994. The purpose of the exhibition was to inform members of the progress on patient education, guidance of diet and exercise treatment, the compliance situation on self-monitoring of blood glucose, self-injection of insulin, etc., in each association. A total of 31 associations including 17 from outside Japan and 14 from Japan participated in this exhibition. ⋯ From these exhibitions we can comprehend the present status of the activities of all the diabetic associations in the world. Especially, an enthusiasm for patient and co-medical staff education in each association was clearly recognized. The total number of visitors including the commercial exhibition during the Congress reached about 17000 people.