Diabetes research and clinical practice
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Diabetes Res. Clin. Pract. · Jul 2018
Multicenter StudyCan trajectories of glycemic control be predicted by depression, anxiety, or diabetes-related distress in a prospective cohort of adults with newly diagnosed type 1 diabetes? Results of a five-year follow-up from the German multicenter diabetes cohort study (GMDC-Study).
The longitudinal association between glycemic control with depression, anxiety or diabetes-related distress in type 1 diabetes is poorly understood. Therefore, we examined long-term trajectories of HbA1c in a new-onset cohort of adults with type 1 diabetes, and analyzed associations with depression, anxiety, and diabetes-related distress. ⋯ We identified distinct trajectories of glycemic control. Depression and anxiety were highly prevalent but they neither predicted 'poor'/'good' glycemic control trajectories nor were they associated with glycemic control at any assessment point.
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Diabetes Res. Clin. Pract. · Dec 2016
Multicenter StudyComorbidity and its relationship with health service use and cost in community-living older adults with diabetes: A population-based study in Ontario, Canada.
This study describes the comorbid conditions in Canadian, community-dwelling older adults with diabetes and the association between the number of comorbidities and health service use and costs. ⋯ Comorbidities in community-living older adults with diabetes are common and associated with a high level of health service use and costs. Accordingly, it is important to use a multiple chronic conditions (not single-disease) framework to develop coordinated, comprehensive and patient-centred programs for older adults with diabetes so that all their needs are incorporated into care planning.
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Diabetes Res. Clin. Pract. · Apr 2015
Randomized Controlled Trial Multicenter StudyHow well do glucose variability measures predict patient glycaemic outcomes during treatment intensification in type 2 diabetes?
Despite links to clinical outcomes in patients with type 2 diabetes mellitus (T2DM), the clinical utility of glycaemic variability (GV) measures is unknown. We evaluated the correlation between baseline GV, and glycated haemoglobin (HbA1c) attainment and hypoglycaemic events during treatment intensification in a large group of patients. ⋯ Pre-treatment GV is associated with glycaemic outcomes in T2DM patients undergoing treatment intensification over 24 weeks. HBGI might be the most robust predictor, warranting validation in dedicated prospective studies or randomized trials to assess the predictive value of measuring GV.
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Diabetes Res. Clin. Pract. · Apr 2015
Multicenter StudyRelationship between primary care visits and hospital admissions in remote Indigenous patients with diabetes: a multivariate spline regression model.
To determine if access to primary health care (PHC) is associated with reduced hospitalisations for remote Indigenous patients with diabetes. ⋯ Using existing empirical data, this study suggests that other things being equal, diabetes patients who had an adequate level of PHC visits are likely to have a lower level of hospitalisations than those with fewer or more PHC visits. This study highlights the importance for remote Indigenous patients with diabetes to have adequate access to PHC.
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Diabetes Res. Clin. Pract. · Apr 2015
Multicenter StudyRace/ethnicity moderates the relationship between chronic life stress and quality of life in type 2 diabetes.
To determine whether chronic life stress is differentially associated with quality of life (QoL) for Blacks vs. Hispanics with type 2 diabetes. ⋯ Black patients with type 2 diabetes may be particularly vulnerable to the deleterious effects of high chronic stress. Social support buffers effects of stress on mental health in Hispanics but not Blacks, which suggests differences in the use and/or quality of social support between Hispanics and Blacks. Longitudinal investigations that examine race/ethnicity, stress, social support, and QoL should help clarify the processes that underlie these observed relations.