Ophthalmic plastic and reconstructive surgery
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Ophthal Plast Reconstr Surg · May 2009
Randomized Controlled TrialReduction of pain and anxiety prior to botulinum toxin injections with a new topical anesthetic method.
To evaluate the safety and efficacy of vapocoolants (topical skin refrigerants) to induce skin anesthesia and relieve patient anxiety and pain prior to cosmetic botulinum injections. ⋯ Vapocoolants represent a safe and effective means to reduce patient discomfort and anxiety before and during botulinum toxin type A treatments for glabellar area indications.