The Journal of international medical research
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Comparative Study Clinical Trial Controlled Clinical Trial
Pain relief in the post-operative period: a comparative trial of morphine and a new analgesic buprenorphine.
In a comparative trial, buprenorphine 0-3 mg or morphine 10 mg was administered intramuscularly to patients post-operatively. The new drug buprenorphine produced more pain relief than morphine and appeared to have a longer duration of action. The side-effects produced by the two drugs were similar, as were the effect on respiratory and cardiovascular measurements.