The Journal of international medical research
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Randomized Controlled Trial
Application of parecoxib in post-uvulopalatopharyngoplasty analgesia.
To investigate the postoperative analgesic effects of parecoxib for uvulopalatopharyngoplasty (UPPP). ⋯ Intravenous parecoxib combined with incision-local ropivacaine provided effective postoperative analgesia for patients with obstructive sleep apnoea syndrome, undergoing UPPP.
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Randomized Controlled Trial Multicenter Study
Pharmacist-led medication education in cancer pain control: a multicentre randomized controlled study in Guangzhou, China.
To evaluate clinical pharmacist-led pain-medication education in patients with cancer. ⋯ Clinical pharmacist-led medication education resulted in improved pain control in patients with cancer.
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Mutations in the high-temperature requirement A serine peptidase 1 (HTRA1) gene were studied in a Chinese family with cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). ⋯ Discovery of a novel missense mutation (c.854C>T) associated with CARASIL expands the known CARASIL-related mutations in HTRA1.
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This institutional anaesthetic practice evaluation compared patient safety with respect to residual neuromuscular blockade (NMB) at the time of tracheal extubation in patients undergoing high-risk eye surgery. ⋯ Residual postoperative curarization at the time of extubation was frequently observed in group M, whereas there was complete recovery in group R/S. Reversal of NMB by sugammadex provides an additional safety dimension to patient care and should thus be considered especially for those at risk of airway complications or aspiration, in addition to frail patients.
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A meta-analysis was conducted to examine the effect of mud therapy on pain relief in patients with knee osteoarthritis (OA). ⋯ Mud therapy is a favourable option for pain relief in patients with knee OA. Additional high-quality randomized controlled trials need to be conducted to explore this issue further and to confirm this conclusion.