The Journal of international medical research
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Randomized Controlled Trial
Effect of heated humidified ventilation on bronchial mucus transport velocity in general anaesthesia: a randomized trial.
To evaluate the effects of heated humidified ventilation on mucociliary function during general anaesthesia. ⋯ Heated humidified ventilation effectively maintains mucociliary clearance of patients during sevoflurane general anaesthesia.
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Randomized Controlled Trial Comparative Study
Effect of ketamine versus alfentanil following midazolam in preventing emergence agitation in children after sevoflurane anaesthesia: a prospective randomized clinical trial.
To investigate the effect of intranasal ketamine versus alfentanil in addition to oral midazolam for the prevention of emergence agitation in children. ⋯ The addition of intranasal ketamine to oral midazolam significantly improved the quality of induction and reduced sevoflurane-induced emergence agitation, in children undergoing urological surgery.
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To investigate emergence times with different fresh gas flow rates, following desflurane anaesthesia. ⋯ These results suggest that there is the potential to predict emergence time based on fresh gas flow rate following desflurane anaesthesia. It should therefore be possible to use a low-flow technique during the emergence period, in addition to the maintenance period, without delaying recovery if the inhaled anaesthetic is stopped at the predicted time before the end of surgery.
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Randomized Controlled Trial
Effect of inhalational anaesthetic on postoperative cognitive dysfunction following radical rectal resection in elderly patients with mild cognitive impairment.
To determine the effect of choice of inhalational anaesthetic (sevoflurane vs propofol) on the incidence and severity of postoperative cognitive dysfunction (POCD) in elderly patients (aged ≥ 60 years) with mild cognitive impairment (MCI). ⋯ There was no difference in the incidence of POCD at 7 days after radical rectal resection under sevoflurane or propofol-based general anaesthesia. Both propofol and sevoflurane were associated with negative cognitive effects, but sevoflurane had a more severe impact on cognitive function than propofol, in elderly patients with MCI.
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Observational Study
Emergence delirium is related to the invasiveness of strabismus surgery in preschool-age children.
To investigate the correlation between preoperative anxiety and emergence delirium (ED), and to identify other factors that contribute to ED (such as invasiveness of surgery), in preschool-age paediatric patients undergoing strabismus surgery. ⋯ Preoperative anxiety was not related to ED in preschool-age paediatric patients undergoing strabismus surgery. The incidence and severity of ED was higher in patients who underwent more complicated strabismus surgery, compared with those undergoing simpler procedures.