The Journal of international medical research
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A secondary exploratory analysis of data from an observational study was used to study the influence of the opioid used for intraoperative anaesthesia on the incidence of post-operative delirium. Patients who had been admitted to the recovery room following elective general anaesthesia were divided into those who had received fentanyl or remifentanil. For unbiased patient analysis, matched pairs were built with respect to gender, age, physical status, anaesthetic type and surgery duration. ⋯ Delirium in the recovery room and on the first post-operative day were both associated with a significantly prolonged post-operative hospital stay. The choice of intraoperative opioid influences the incidence of post-operative delirium. Remifentanil was associated with a lower incidence of post-operative delirium in the early post-operative period.
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The usefulness of the Revised Injury Severity Classification (RISC) analysis was compared with that of the Trauma and Injury Severity Score (TRISS) for evaluating the quality of treatment of severely injured patients at the General Hospital Celje, Slovenia. Over a period of 2 years, data from a cohort of 155 patients treated at the General Hospital Celje were included in the Traumaregister Deutsche Gesellschaft für Unfallchirurgie. The structure of the patient group was compared with that in the registry, and TRISS and RISC analyses were performed. ⋯ Evaluation of RISC (area under the curve [AUC] 0.94, Hosmer-Lemeshow test 3.5) demonstrated the efficacy of this method in the patient group. TRISS (AUC 0.89, Hosmer-Lemeshow test 21.1) was not a reliable instrument for analysis of treatment of major trauma patients. We believe that RISC should replace TRISS for evaluation of the treatment of major trauma patients.
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Randomized Controlled Trial
Intraperitoneal ropivacaine for effective pain relief after laparoscopic appendectomy: a prospective, randomized, double-blind, placebo-controlled study.
This prospective, randomized, doubleblind, placebo-controlled study evaluated the effectiveness of intraperitoneal instillation of ropivacaine in the relief of pain in patients undergoing laparoscopic appendectomy. Patients in group C (placebo control group; n = 33) received normal saline and those in group I (instillation group; n = 30) received an instillation of 2 mg/kg ropivacaine at the initiation of the pneumoperitoneum. ⋯ Thus, intraperitoneal ropivacaine instillation reduced pain during the post-operative period after laparoscopic appendectomy. In addition, this drug was easy to administer and had no adverse effects at the dose used.
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This study investigated the quality of documentation of post-operative nausea and vomiting (PONV) by comparing incidences collected by a research team with those reported routinely by nursing personnel. A total of 560 patients passing through an interdisciplinary recovery room were included in the study. The overall recorded incidence of PONV over 24 h was 30.7%, which was in agreement with the predicted value of 32% calculated using incidences from published randomized controlled trials. ⋯ In conclusion, PONV in routine clinical care is likely to be under-reported. To use PONV as a valid quality measure, patients need to be actively asked about nausea and vomiting at frequent intervals in a standardized fashion. A considerable proportion of patients experience PONV after discharge from the recovery room, so the assessment of PONV should cover at least 24 h post-operatively.
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Case Reports
Malignant atrophic papulosis with severe gastrointestinal perforation and omental necrosis: a case report.
Malignant atrophic papulosis (MAP) is a rare disease with an extremely grim prognosis, death being due to gastrointestinal perforation and neurological disorders. We report a severe case of MAP in a 37-year old woman. ⋯ Pathological findings revealed MAP. Surgical intervention was successful and the patient recovered smoothly but later died of malnutrition and septicaemia.