The Journal of international medical research
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Randomized Controlled Trial Comparative Study Clinical Trial
Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial.
To investigate the efficacy of pretreatment with cisatracurium for prevention of pain associated with propofol injection, and compare its efficacy with that of lidocaine. ⋯ 0.15 mg/kg cisatracurium effectively decreases the incidence and severity of pain induced by propofol injection without any significant complications.
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Randomized Controlled Trial Comparative Study
Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy.
To investigate the efficacy and safety of sedation with dexmedetomidine in upper gastrointestinal endoscopy. ⋯ Dexmedetomidine has a good safety profile and is an effective sedative for use in upper gastrointestinal endoscopy.
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Randomized Controlled Trial Comparative Study
Intravenous lidocaine pretreatment with venous occlusion for reducing microemulsion propofol induced pain: comparison of three doses of lidocaine.
Pretreatment with intravenous 40 mg or 0.5 mg/kg lidocaine with venous occlusion is recommended to prevent pain following injection of lipid emulsion propofol. This approach is not sufficient to prevent pain from the injection of microemulsion propofol. The present study investigated whether a higher dose of lidocaine pretreatment with venous occlusion would be more effective for reducing pain following injection of microemulsion propofol compared with 40 mg lidocaine. ⋯ Pretreatment with 60 mg lidocaine intravenously with venous occlusion may be the most effective minimum dose for reducing injection pain following microemulsion propofol administration for induction of anaesthesia.
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Randomized Controlled Trial Clinical Trial
EMLA(R) cream: a pain-relieving strategy for childhood vaccination.
To evaluate the effectiveness of topical eutectic mixture of local anaesthetics (EMLA®) cream in reducing the pain associated with vaccination injections. ⋯ Application of EMLA® cream can be effectively incorporated as a routine pain-relieving intervention within routine vaccination appointments.
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Randomized Controlled Trial Comparative Study
Intrathecal bupivacaine or levobupivacaine: which should be used for elderly patients?
To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged ≥ 65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). ⋯ These current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥ 65 years of age undergoing elective TUR-P or TUR-M operations.