The Journal of international medical research
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Randomized Controlled Trial
Influence of goal-directed therapy with balanced crystalloid-colloid or unbalanced crystalloid solution on base excess.
To investigate changes in standard base excess (SBE) when administering two different infusion regimens for elective hip replacement within a goal-directed haemodynamic algorithm. ⋯ SBE decreased in the unbalanced group without influence on fluid requirements and haemodynamic stability.
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Randomized Controlled Trial Clinical Trial
Efficacy of intraperitoneal and intravenous lidocaine on pain relief after laparoscopic cholecystectomy.
This randomized, double-blind, placebo-controlled trial evaluated intraperitoneal (IP) lidocaine administration and intravenous (IV) lidocaine infusion for postoperative pain control after laparoscopic cholecystectomy (LC). ⋯ The IP administration of lidocaine and IV lidocaine infusion significantly reduced postoperative pain and opioid consumption in LC patients, compared with control infusions. For convenience, IV lidocaine could be used for pain reduction following LC; IP administration places additional burden on the surgeon.
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Randomized Controlled Trial Comparative Study Clinical Trial
Cisatracurium pretreatment with tourniquet reduces propofol injection pain: a double-blind randomized controlled trial.
To investigate the efficacy of pretreatment with cisatracurium for prevention of pain associated with propofol injection, and compare its efficacy with that of lidocaine. ⋯ 0.15 mg/kg cisatracurium effectively decreases the incidence and severity of pain induced by propofol injection without any significant complications.
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Randomized Controlled Trial Comparative Study
Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy.
To investigate the efficacy and safety of sedation with dexmedetomidine in upper gastrointestinal endoscopy. ⋯ Dexmedetomidine has a good safety profile and is an effective sedative for use in upper gastrointestinal endoscopy.
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To investigate the effects of sociodemographic factors and maternal anxiety levels on behaviour in children undergoing surgery. ⋯ Maternal knowledge and experience of anaesthesia, and high levels of maternal anxiety, may be related to increased anxiety in children undergoing surgery.