Journal of cataract and refractive surgery
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J Cataract Refract Surg · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialTopical anesthesia with pH-adjusted versus standard lidocaine 4% for clear corneal cataract surgery.
To evaluate and compare the efficacy of a sodium-bicarbonate-adjusted preparation of lidocaine 4% (pH = 7.2) and standard lidocaine (pH = 5.2) for topical anesthesia in clear corneal cataract surgery. ⋯ In this study, pH-adjusted lidocaine 4% was a safe, effective topical anesthetic for clear corneal surgery and had minimal local and systemic toxicity. Administration of pH-adjusted lidocaine 4% resulted in significantly higher aqueous humor lidocaine concentrations than administration of standard lidocaine 4%.
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J Cataract Refract Surg · Nov 1997
Randomized Controlled Trial Comparative Study Clinical TrialShort-term effects of flurbiprofen and diclofenac on refractive outcome and corneal haze after photorefractive keratectomy.
To evaluate the short-term effects of topical nonsteroidal anti-inflammatory drugs (NSAIDs) on refractive outcome and corneal haze after excimer laser photorefractive keratectomy (PRK) according to the degree of myopia and to compare the results with those of topical steroids. ⋯ Topical NSAIDs were less effective than topical steroids in reducing myopic regression and haze after PRK, especially in highly myopic eyes.