Clinical endocrinology
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Clinical endocrinology · May 2008
Comparative StudyInsulin resistance and body composition in preterm born children during prepubertal ages.
Premature born children may show insulin resistance in childhood which may be due to intrauterine or postnatal adverse environmental factors. ⋯ Premature born AGA and SGA children do not have insulin resistance when compared to term children if they have made a catch-up growth appropriate for their target height and have normal BMI. The similar insulin levels in preterm SGA and preterm AGA children together with increased insulin levels in term SGA children points to the fact that it is the intrauterine restriction in the third trimester that has an adverse effect on future adverse metabolic outcome.