Clinical endocrinology
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Clinical endocrinology · Oct 2016
Prevalence and correlates of vitamin D deficiency in adults after traumatic brain injury.
Traumatic brain injury (TBI) is a major cause of long-term disability with variable recovery. Preclinical studies suggest that vitamin D status influences the recovery after TBI. However, there is no published clinical data on links between vitamin D status and TBI outcomes. The aim was to determine the (i) prevalence of vitamin D deficiency/insufficiency, and associations of vitamin D status with (ii) demographic factors and TBI severity, and with (iii) cognitive function, symptoms and quality of life, in adults after TBI. ⋯ Vitamin D deficiency is common in patients after TBI and associated with impaired cognitive function and more severe depressive symptoms.