Journal of pain and symptom management
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J Pain Symptom Manage · Feb 2016
Validation of the Modified Glasgow Prognostic Score in Advanced Cancer Patients Receiving Palliative Care.
The modified Glasgow Prognostic Score (mGPS) is a well-known marker of systemic inflammatory response previously associated with poor prognoses in cancer. ⋯ Systemic inflammatory response is associated with a low functional status, primary lung cancers, and tumors with hepatic metastasis. When starting PC, an mGPS definition may have clinical utility implications, by identifying three groups of patients with advanced cancer patients with distinct survival outcomes.
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J Pain Symptom Manage · Feb 2016
Review Meta AnalysisGender Differences in Hiccup Patients: Analysis of Published Case Reports and Case-Control Studies.
Although sporadic male predominance in hiccup patients has been reported, the association between gender differences and triggering factors has rarely been evaluated in patients with hiccups. ⋯ We demonstrated male predominance in hiccup patients. This gender difference for hiccups was more pronounced in patients with non-CNS causes, whereas indistinct in patients with CNS causes.
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J Pain Symptom Manage · Feb 2016
Multicenter Study Observational StudyThe Burden of Polypharmacy in Patients Near the End of Life.
Patients with advanced illness are prescribed multiple medications in the last year of life, intensifying the risk of negative consequences related to polypharmacy. ⋯ There is a significant medication burden placed on patients with advanced illness. Although most medications were prescribed for supportive care, we observed a high prevalence of medications for managing non-life-threatening comorbidities.