Journal of pain and symptom management
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J Pain Symptom Manage · Aug 2021
Randomized Controlled TrialFixed-Dose Netupitant and Palonosetron for Chronic Nausea in Cancer Patients: A Double-Blind, Placebo Run-In Pilot Randomized Clinical Trial.
No clinical trials have examined the effect of netupitant/palonosetron (NEPA) on chronic nausea in patients with cancer. ⋯ NEPA and placebo were associated with similar magnitude of within-group improvement in chronic nausea without significant between-group differences (Clinicaltrials.gov NCT03040726).
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J Pain Symptom Manage · Aug 2021
ReviewA scoping review of end-of-life communication in international palliative care guidelines for acute care settings.
End-of-life communication in acute care settings can be challenging and many patients and families have reported low satisfaction with those conversations. ⋯ Palliative and end-of-life guidelines applicable to acute care settings outline the purpose of end-of-life communication and address how, when, and by whom such conversations are best initiated and facilitated. How guidelines are developed and what aspects of communications are included and emphasized may differ across countries related to role differences of physicians and nurses and national laws and regulations.
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J Pain Symptom Manage · Aug 2021
Randomized Controlled TrialPredictors of Response to an Evidence-based Behavioral Cancer Pain Management Intervention: An Exploratory Analysis from a Clinical Trial.
Interventions that teach patients cognitive and behavioral strategies for managing cancer pain have demonstrated effectiveness. Systematic reviews of such interventions call for research to inform their implementation in practice, including investigations into which patients are most likely to benefit. ⋯ Our findings elucidate several subgroups of patients who may be especially likely to benefit from PCST, informing both targeted implementation efforts and opportunities to improve delivery for diverse patients.
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J Pain Symptom Manage · Aug 2021
Fatigue, Stress, and Functional Status Are Associated with Taste Changes in Oncology Patients Receiving Chemotherapy.
A common complaint among oncology patients receiving chemotherapy is altered taste perception. ⋯ This study provides new evidence on associations between taste changes and common co-occurring symptoms and stress in oncology patients receiving chemotherapy. Clinicians need to evaluate for taste changes in these patients because this symptom can effect patients' nutritional intake and quality of life.
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J Pain Symptom Manage · Aug 2021
Randomized Controlled TrialPalliative Long-term Abdominal Drains Versus Large Volume Paracentesis in Refractory Ascites due to Cirrhosis (REDUCe Study): Qualitative Outcomes.
Palliative care remains suboptimal in end-stage liver disease (ESLD). ⋯ Patients and nurses expressed acceptability of palliative LTAD in ESLD and preference for this approach in enabling care at home. Proceeding to a definitive trial is feasible.