Journal of pain and symptom management
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J Pain Symptom Manage · Oct 2022
Inflammatory markers and radiotherapy response in patients with painful bone metastases.
Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT efficacy in patients with painful bone metastases. ⋯ Results from this study show an association between RT response and change in pro-inflammatory mediators and indicate that inflammation may be important to achieve an analgesic RT response in patients with painful bone metastases. None of the investigated inflammatory markers were found to be pre-treatment predictors of RT response.
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J Pain Symptom Manage · Oct 2022
Admission Code Status and End-of-life Care for Hospitalized Patients with COVID-19.
The COVID-19 pandemic has highlighted variability in intensity of care. We aimed to characterize intensity of care among hospitalized patients with COVID-19. ⋯ In this international cohort of patients with COVID-19, Full Code was the initial code status in the majority, and more likely among patients who were Black or Asian race, Hispanic ethnicity or male. These results provide direction for future studies to improve these disparities in care.
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J Pain Symptom Manage · Oct 2022
National End-of-Life-Treatment Preferences are stable over time: National Health and Aging Trends Study.
Advance Care Planning is a process of understanding and sharing preferences regarding future medical care. ⋯ We found that national trends in preferences for end-of-life treatment did not substantially change over time and may be stable within individual older adults.
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J Pain Symptom Manage · Oct 2022
Integrated primary palliative care in Nigeria- perspectives of patients, families and providers.
Palliative care should be integrated into primary healthcare systems within low- and middle-income countries to achieve Universal Health Coverage goals. We aimed to identify preferences and expectations for primary palliative care among people living with serious illness and their families and the readiness of primary healthcare providers to deliver primary palliative care in Nigeria. ⋯ Our findings have identified specific approaches to implement the WHO policy on integrated primary palliative care. Palliative care integration within primary healthcare in Nigeria can be achieved through building information and communication skills of healthcare providers, engaging and empowering patients to exercise their agency in care decisions, and adequately delineating healthcare providers' roles to ensure staff work within their competencies and training.