Journal of pain and symptom management
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J Pain Symptom Manage · Nov 2022
ReviewSubcutaneous drugs and off-label use in hospice and palliative care: a scoping review.
Subcutaneous drug administration is an interesting approach for symptom control in hospice and palliative care. However, most drugs have no marketing authorization for subcutaneous administration and are therefore used off-label. In order to meet the requirements of a safe and effective drug therapy, especially in highly vulnerable patients, it is essential to investigate the scope of evidence of these common practices. ⋯ This work provides an overview of current evidence on subcutaneous and off-label used drugs in hospice and palliative care. Although both are common practices, evidence on tolerability and effectiveness, particularly pharmacokinetic data, is limited and the identified information gaps need to be closed. This work establishes a basis for further research in this area.
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J Pain Symptom Manage · Nov 2022
ReviewLife Review Intervention: A Systematic Review of Its Feasibility among Persons with Cancer.
Life Review Intervention (LRI) has started to shift in emphasis of focus onto persons with cancer and its effectiveness in improving their psychological well-being. The process has now begin integrating into healthcare settings as a complementary treatment for this population. ⋯ LRI is feasible to be implemented among persons with cancer, given the high acceptability and availability of resources for its implementation. The present review highlighted the preliminary knowledge on the feasibility of the intervention.
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J Pain Symptom Manage · Nov 2022
Randomized Controlled TrialVulnerability and Resilience: Phenomenological Analysis of Cancer Patients Value Directives.
Personal values are individual conceptions of the desirable appraisals and actions that guide our attitudes and behaviour. Advance care planning (ACP) now emphasises the consideration of personal life goals and values expressed as a Values Directive (VD) to guide discussions concerning medical treatment. ⋯ Cancer patients seek to make meaning of their experiences, concurrently posturing vulnerability and resilience, despite conflicting emotions and experiences. Given that the choices people make as they approach dying relate to their most deeply held values, ACP conversations should explore how patients draw from their values and life goals to optimise their adaptations to illness.