Journal of pain and symptom management
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J Pain Symptom Manage · Oct 2010
Randomized Controlled Trial Multicenter StudyContribution of a heating element to topical anesthesia patch efficacy prior to vascular access: results from two randomized, double-blind studies.
Pain associated with superficial procedures, including intravenous (IV) access procedures, should be prevented when possible, especially in children. ⋯ Heated patches provided significantly better pain relief compared with unheated patches. All the subjects tolerated the patches well, with few adverse effects.
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J Pain Symptom Manage · Aug 2010
Randomized Controlled Trial Comparative StudyA randomized, double-blind, double-dummy comparison of the efficacy and tolerability of low-dose transdermal buprenorphine (BuTrans seven-day patches) with buprenorphine sublingual tablets (Temgesic) in patients with osteoarthritis pain.
Osteoarthritis (OA) is a common cause of chronic pain, particularly in the older population. Modern approaches to the management of OA pain recommend tailoring treatment to the individual. This study examines treatment options for OA pain in the form of low-dose transdermal and sublingual opioid analgesia. ⋯ In conclusion, seven-day, low-dose transdermal buprenorphine patches are as effective as sublingual buprenorphine, with a better tolerability profile.
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J Pain Symptom Manage · Aug 2010
Randomized Controlled TrialDoes recall period have an effect on cancer patients' ratings of the severity of multiple symptoms?
Choosing an appropriate recall period for symptom assessment in a clinical trial is dependent on the design and purpose of the trial. ⋯ This study demonstrated that the MDASI in a seven-day recall format has psychometric properties consistent with the 24-hour recall version, which may promote its use in future cancer clinical trials and may inform the choice of recall period when symptoms are outcome measures.
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J Pain Symptom Manage · Aug 2010
Randomized Controlled TrialEfficacy of an intervention for fatigue and sleep disturbance during cancer chemotherapy.
Multiple complex symptoms from cancer treatment can interfere with functioning. ⋯ Potential explanations include high variability and/or floor effect for fatigue, incorrect timing of measures, insufficient amount or dose of the intervention, and confounding effects of gender. Future research should consider screening for symptom severity and tailoring interventions.
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J Pain Symptom Manage · Jul 2010
Randomized Controlled TrialA randomized controlled trial of a standardized educational intervention for patients with cancer pain.
Published literature has not defined the effectiveness of standardized educational tools that can be self-administered in the general oncology population with pain. ⋯ Provision of a video and/or booklet for people with cancer pain was a feasible and effective adjunct to the management of cancer pain.