International journal of colorectal disease
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Int J Colorectal Dis · Jun 2011
Randomized Controlled TrialSedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol.
The use of sedatives during colonoscopy remains controversial because of its safety concerns. We compared cardiorespiratory function and sedative and analgesic effects in sedative colonoscopy, using combinations of midazolam with either fentanyl or propofol. ⋯ The combination of midazolam with either fentanyl or propofol allowed patients to undergo colonoscopy under comparable sedative and analgesic conditions. The combination with fentanyl had a significantly lower effect on pulse rate and blood pressure. The combination with propofol produced superior amnestic effects.