International journal of colorectal disease
-
Int J Colorectal Dis · Aug 2012
The effect of fibrin glue on the early healing phase of intestinal anastomoses in the rat.
Protecting the anastomotic integrity using suture or staple line reinforcement remains an important goal for ongoing research. The present comprehensive study aims to establish the effects of fibrin glue on the early phase of anastomotic healing in the rat intestine. ⋯ There is no justification for using fibrin glue on patent anastomoses constructed under low-risk conditions. Its potential benefit under conditions where chances for anastomotic leakage are enhanced needs further investigation.