Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jul 2013
Randomized Controlled Trial Comparative StudyHemodynamic effects of continuous versus bolus infusion of terlipressin for portal hypertension: a randomized comparison.
The hemodynamics of patients with portal hypertension within 4 h after a single injection of terlipressin has been studied. However, the hemodynamics in a longer phase under different infusion styles is unknown. This study aims to compare the effects of bolus and continuous infusion of terlipressin on systemic and hepatic hemodynamics in patients with portal hypertension. ⋯ Continuous infusion of terlipressin reduces PVP stably and may become an alternative to traditional bolus injection.