Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jan 2021
Meta AnalysisEffects of the herbal medicine Rikkunshito, for functional dyspepsia: A systematic review and meta-analysis.
Functional dyspepsia (FD) is characterized by chronic and unexplained indigestion at upper abdomen. Because of unsatisfactory effect of conventional treatments, demand is growing for complementary and alternative medicine. Rikkunshito (RKT) is a herbal medicine, which has been widely used for FD in Asia; however, the evidence is lacking. We carried out systematic review and meta-analysis to evaluate the effect and safety of RKT in the treatment of FD. ⋯ Rikkunshito and combination therapy might be considered an effective alternative treatment for FD. Further rigorously designed and high-quality RCTs are needed.