Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jul 2013
Meta AnalysisChewing gum reduces postoperative ileus following abdominal surgery: a meta-analysis of 17 randomized controlled trials.
Chewing gum proposal has been used in surgery to reduce postoperative ileus for more than 10 years; however, the efficacy remains imprecise. The aim of this study was to accurately assess whether the use of the chewing gum could reduce duration of postoperative ileus following the abdominal surgery. ⋯ Results of the meta-analysis suggest that chewing gum following abdominal surgery offers benefits in reducing the time of postoperative ileus.
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J. Gastroenterol. Hepatol. · May 2013
Value of hepatic subcapsular flow by color Doppler ultrasonography in the diagnosis of biliary atresia.
Diagnosis of biliary atresia (BA), particularly distinguishing it from other causes of neonatal cholestasis (NC), is challenging. Ultrasonography is a helpful investigation when evaluating NC. The aim was to determine the value of color Doppler ultrasound, particularly hepatic subcapsular flow, as a possible tool in early discrimination of BA from other causes of NC. ⋯ Color Doppler ultrasound findings could help significantly in discriminating BA from other causes of NC, among which hepatic subcapsular flow had the best performance. Considering the young age of BA patients (61.8 ± 15.1 days), hepatic subcapsular flow can help in early diagnosis of BA and prevent the delay in surgical correction.
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J. Gastroenterol. Hepatol. · Apr 2013
Assessing the cost-effectiveness of treating chronic hepatitis C virus in people who inject drugs in Australia.
To assess the cost-effectiveness of hepatitis C virus treatment with pegylated interferon alfa-2a and ribavirin in current and former people who inject drugs (PWID). ⋯ Despite comorbidities, increased mortality, and reduced adherence, treatment of both current and former PWID is cost-effective. Our estimates fall below the unofficial Australian cost-effectiveness threshold of $AUD 50,000 per QALY for public subsidies. Scaling up treatment for PWID can be justified on purely economic grounds.
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J. Gastroenterol. Hepatol. · Mar 2013
Multicenter Study Comparative Study Clinical TrialHistology of symptomatic gastroesophageal reflux disease: is it predictive of response to proton pump inhibitors?
To examine the differences in esophageal histopathology between non-erosive reflux disease (NERD) and reflux esophagitis (RE), and to investigate whether baseline esophageal histopathology can predict the therapeutic response to proton pump inhibitors (PPIs). ⋯ The therapeutic efficacy of PPI can be predicted from the features of biopsied esophageal tissue. Factors predictive of resistance to treatment with PPI are negativity for PGP 9.5 in NERD patients and intraepithelial bleeding in RE patients.