Revista clínica española
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Revista clínica española · Oct 1995
Review Comparative Study[Changes in epidemiology of opportunistic infections due to Candida].
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Revista clínica española · Oct 1995
Review Comparative Study[Superficial mycoses in immunosuppressed patients].
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Revista clínica española · Oct 1995
[The effect of surgical antibiotic prophylaxis and the timing of its administration on the risk of surgical wound infection].
Clinical trials have demonstrated the efficacy of surgical prophylaxis (SP). Nevertheless, how the timing of antibiotic administration influences the risk of infection in clinical praxis has scarcely been studied. In this study an assessment was made of whether the non administration of antibiotic, or its administration longer than 2 hours preoperatively, or only postoperatively, are associated with a higher rate of infection of the surgical wound (SWI) compared with antibiotic administration within the two hours prior to surgery in our setting. ⋯ The administration of SP is inappropriate in a high percentage of cases. The administration of SP within the 2 hours prior to surgery reduces the risk of SWI, compared with the administration 2 hours or longer prior to intervention or only postoperatively.