Revista clínica española
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Revista clínica española · Feb 2007
Comparative Study[Current role of statins in the stroke prevention].
The role of lipids in stroke has been a traditionally debated subject. Many studies have recently demonstrated that reduction of cholesterol levels is associated to a lower stroke incidence. At present, statins play an essential role in both primary as well as secondary stroke prevention. More knowledge on the use of statins in stroke in order to be able to apply it in the daily clinical practice is needed.
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Revista clínica española · Dec 2006
[New, relevant and practical aspects of the treatment of neuropathic pain].
In the Spanish population it is difficult to calculate the prevalence of neuropathic pain (NP) although it is estimated that it is present in 40% of the cases of chronic pain. The treatment is not easy and we must choose between the different drugs, the most appropriate taking into account the effectivity in data from clinical trials, releaf of comorbidities associated to NP and less side effects. ⋯ In this work, the author recommends antiepileptic drugs, like gabapentin and pregabalin as first choice treatments. Amitriptiline, a tricycle antidepressant and opioids must be used only when there is a lack of response or intolerance.
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The participation of genetic and environmental factors has always been invoked in the pathogenesis of the autoimmune systemic diseases, including the primary vasculitides. Among the environmental factors, infections, fundamentally those having a viral nature, have always been focused on, especially after the discovery of the close existing relationship between the polyarteritis nodosa and the hepatitis B virus, on the one hand, and mixed cryoglobulinemia and the hepatitis C virus, on the other. The present review summarizes data from the most recent literature related to associations between virus infections and primary vasculitides, following the Chapel-Hill vasculitis classification.
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In this article we briefly review the evidence on the effect of different "natural" products on cholesterolemia. Plant stanols and sterols reduce cholesterol intestinal absorption and decrease total and LDL cholesterol by approximately 10%. Polycosanol is a mixture of saturated alcohols that seem to inhibit cholesterol hepatic synthesis and decrease total and LDL cholesterol by up to 25%. The effects on the cholestorolemia of soy and soluble fiber are modest.