Pediatric surgery international
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Pediatr. Surg. Int. · Feb 2010
Comparative StudyApplication with repeated serum biomarkers in pediatric appendicitis in clinical surgery.
To apply the repeated serum laboratory tests in diagnosing acute appendicitis in children with suspected appendicitis. ⋯ Significant change between primary and repeated serum laboratory tests may serve as a helpful method in predicting acute appendicitis in children with suspected appendicitis.
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Pediatr. Surg. Int. · Feb 2010
Application with repeated serum biomarkers in pediatric appendicitis in clinical surgery.
From 2005 to 2007, we prospectively collected 217 pediatric patients with clinically suspected appendicitis. The repeated serum laboratory tests were measured 6 h later and the changes in serum inflammatory biomarkers analyzed. Significant changes in serum parameters between primary and repeated examinations were selected as the discriminating variables. The receiver operating characteristic (ROC) curves were used to determine the cutoff values of the changes between two examinations in predicting appendicitis. ⋯ Significant change between primary and repeated serum laboratory tests may serve as a helpful method in predicting acute appendicitis in children with suspected appendicitis.
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Pediatr. Surg. Int. · Feb 2010
Comparative StudyEffect of polymyxin B-immobilized fiber hemoperfusion on respiratory impairment, hepatocellular dysfunction, and leucopenia in a neonatal sepsis model.
Sepsis and septic shock remain a major source of morbidity and mortality in neonates despite advances in antimicrobials and aggressive supportive care. Our aim was to study the effects of polymyxin-B direct hemoperfusion (PMX-DHP) therapy on sepsis-induced respiratory impairment, liver dysfunction and leucopenia in a neonatal cecal ligation and perforation (CLP) model. ⋯ PMX-DHP therapy limited the respiratory impairment, liver dysfunction and leucopenia in a neonatal septic model, which resulted in an improvement of survival time.