Pediatric surgery international
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Pediatr. Surg. Int. · Mar 2010
Use of a combined oxygen/nitrous oxide/morphine chlorydrate protocol for analgesia in burned children requiring painful local care.
We present the results of the use of a protocol of inhalational oxygen/nitrous oxide mixtures associated with oral opioids on a prospective cohort of 33 children undergoing local care for acute but limited burned skin lesions. ⋯ Our study demonstrates that the use of a simple protocol of inhalational oxygen/nitrous oxide mixtures associated with oral opioids could be safe and effective. This association was well tolerated without any adverse effect.
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Pediatr. Surg. Int. · Mar 2010
Pediatric tracheostomy: complications and role of home care in a developing country.
Tracheotomy in its earlier days was most commonly performed for acute airway infection in children. Its indications are now changing; it is now most commonly performed for congenital malformations (McMurray and Prescott in Practical pediatric otolaryngology. W.B. Saunders Company, Philadelphia, pp 575-592, 1996). This shift in indication has increased the rate of survival of such patients, and therefore the number of children going home after tracheostomy has also increased. ⋯ A large number of tracheostomies have been performed in the PV group to reduce the intensive care unit (ICU) stay and to prevent nosocomial infections. The need arises from the high cost of prolonged stay in an ICU setup, which is a cause of major economic burden, and lack of financial assistance for these patients worsens the scenario. Home care of the tracheostomy tubes remains a good option for patients requiring long periods of time to overcome their primary pathology.
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Pediatr. Surg. Int. · Feb 2010
Comparative StudyApplication with repeated serum biomarkers in pediatric appendicitis in clinical surgery.
To apply the repeated serum laboratory tests in diagnosing acute appendicitis in children with suspected appendicitis. ⋯ Significant change between primary and repeated serum laboratory tests may serve as a helpful method in predicting acute appendicitis in children with suspected appendicitis.
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Pediatr. Surg. Int. · Feb 2010
Application with repeated serum biomarkers in pediatric appendicitis in clinical surgery.
From 2005 to 2007, we prospectively collected 217 pediatric patients with clinically suspected appendicitis. The repeated serum laboratory tests were measured 6 h later and the changes in serum inflammatory biomarkers analyzed. Significant changes in serum parameters between primary and repeated examinations were selected as the discriminating variables. The receiver operating characteristic (ROC) curves were used to determine the cutoff values of the changes between two examinations in predicting appendicitis. ⋯ Significant change between primary and repeated serum laboratory tests may serve as a helpful method in predicting acute appendicitis in children with suspected appendicitis.
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Pediatr. Surg. Int. · Feb 2010
Comparative StudyEffect of polymyxin B-immobilized fiber hemoperfusion on respiratory impairment, hepatocellular dysfunction, and leucopenia in a neonatal sepsis model.
Sepsis and septic shock remain a major source of morbidity and mortality in neonates despite advances in antimicrobials and aggressive supportive care. Our aim was to study the effects of polymyxin-B direct hemoperfusion (PMX-DHP) therapy on sepsis-induced respiratory impairment, liver dysfunction and leucopenia in a neonatal cecal ligation and perforation (CLP) model. ⋯ PMX-DHP therapy limited the respiratory impairment, liver dysfunction and leucopenia in a neonatal septic model, which resulted in an improvement of survival time.