Journal of critical care
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Journal of critical care · Oct 2015
Multicenter StudyPostintubation hypotension in intensive care unit patients: A multicenter cohort study.
To determine the incidence of postintubation hypotension (PIH) and associated outcomes in critically ill patients requiring endotracheal intubation. ⋯ The development of PIH is common in ICU patients requiring emergency airway control and is associated with poor patient outcomes.
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Journal of critical care · Oct 2015
Multicenter Study Observational StudySepsis may not be a risk factor for mortality in patients with acute kidney injury treated with continuous renal replacement therapy.
We aimed to study the clinical characteristics, courses, and outcomes of critically ill patients with septic acute kidney injury (AKI) treated with continuous renal replacement therapy (CRRT) in comparison with nonseptic AKI treated with CRRT. ⋯ Sepsis may not be a risk factor for mortality in patients with AKI whose condition has become severe enough to require CRRT.
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Journal of critical care · Oct 2015
Randomized Controlled Trial Multicenter StudyImproving rehabilitation after critical illness through outpatient physiotherapy classes and essential amino acid supplement: A randomized controlled trial.
Patients recovering from critical illness may be left with significant muscle mass loss. This study aimed to evaluate whether a 6-week program of enhanced physiotherapy and structured exercise (PEPSE) and an essential amino acid supplement drink (glutamine and essential amino acid mixture [GEAA]) improves physical and psychological recovery. ⋯ Enhanced rehabilitation combined with GEAA supplement may enhance physical recovery and reduce anxiety and depression.
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Journal of critical care · Oct 2015
Multicenter StudySustained low-efficiency dialysis with regional citrate anticoagulation in medical intensive care unit patients with liver failure: a prospective study.
Patients with liver failure requiring dialysis are at increased risk for citrate accumulation during sustained low-efficiency dialysis (SLED). The aim of this study was to evaluate the feasibilty of citrate SLED in critical ill patients with liver failure and investigate predictive parameters regarding citrate accumulation. ⋯ Despite substantial accumulation of citrate in serum, SLED is save and feasible in patients with liver failure using a citrate anticoagulation. Careful monitoring of electrolytes and acid base status is mandatory to ensure patient safety.
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Journal of critical care · Oct 2015
Multicenter Study Observational StudyDecrease of oxidative phosphorylation system function in severe septic patients.
The comparison of oxidative phosphorylation system capacities between septic patients and control subjects has been scarcely analyzed and only in studies with small sample size (fewer than 40 septic patients and 40 controls). Thus, the objective of this study was to compare platelet respiratory complex IV (CIV) activity between severe septic patients and healthy individuals in a larger series (including 198 severe septic patients and 96 healthy controls). ⋯ The major finding of our work, involving the largest series to date of severe septic patients with data on oxidative phosphorylation system capacity, was that surviving and nonsurviving septic patients showed lower platelet CIV-specific activity during the first week of sepsis than healthy controls.