Journal of critical care
-
Journal of critical care · Oct 2017
Review Meta AnalysisIntubation using apnoeic oxygenation to prevent desaturation: A systematic review and meta-analysis.
To determine whether or not apnoeic oxygenation reduces the incidence of hypoxaemia during endotracheal intubation. ⋯ In patients whom are being intubated for any indication other than respiratory failure, apnoeic oxygenation at any flow rate 15L or greater is likely to reduce their incidence of desaturation (<90%) and critical desaturation (<80%). However, further high quality RCTs are required given the high degree of heterogeneity in many of the outcomes and subgroup analyses.
-
Journal of critical care · Oct 2017
Experience using high-dose glucose-insulin-potassium (GIK) in critically ill patients.
To audit the use of GIK in terms of safety, haemodynamic effects, and impact on catecholamine dosage. ⋯ High-dose GIK can be safely used in critically ill patients, though blood glucose and potassium levels must be monitored frequently. GIK was associated with improved CI and blood lactate levels. Impact on survival requires prospective evaluation.
-
Journal of critical care · Oct 2017
Review Meta AnalysisRespiratory support techniques to avoid desaturation in critically ill patients requiring endotracheal intubation: A systematic review and meta-analysis.
To evaluate which respiratory support method for critically ill patients undergoing endotracheal intubation (ETI) is associated with less desaturation. ⋯ ApOx was significantly associated with higher minimum SpO2 registered during the intubation procedure. Further studies are needed to increase the number of included patients and demonstrate the benefit of ApOx and of other respiratory support methods (e.g. NIV, HFNC).
-
Journal of critical care · Oct 2017
Review Meta AnalysisSystematic review and meta-analysis of renal replacement therapy modalities for acute kidney injury in the intensive care unit.
To compare clinical outcomes among critically ill adults with acute kidney injury (AKI) treated with continuous renal replacement therapy (CRRT), intermittent hemodialysis (IHD) or sustained low efficiency dialysis (SLED). ⋯ We did not find a definitive advantage for any RRT modality on short-term patient or kidney survival. Well-designed, adequately-powered trials are needed to better define the role of RRT modalities for treatment of critically ill patients with AKI.
-
Journal of critical care · Oct 2017
Observational StudyThe impact of delayed rapid response call activation on patient outcomes.
To investigate the impact of delay in rapid response call (RRC) activation on Hospital mortality. ⋯ A delay of ≥15min was associated with significantly increased in-hospital mortality and longer hospitalization. The factors contributing to the observed increase in mortality with delayed RRCs require further exploration.