Journal of critical care
-
Journal of critical care · Oct 2017
Serum lactate dehydrogenase is predictive of persistent organ failure in acute pancreatitis.
Elevated serum lactate dehydrogenase (LDH) has been reported in a serious of clinical diseases. However, the relationship between LDH and the incidence of persistent organ failure (POF) in acute pancreatitis (AP) has not been characterized. ⋯ Our results indicate that serum LDH on admission is independently associated with POF in AP and may serve as a potential prognostic factor.
-
Journal of critical care · Oct 2017
Management of ventilator associated pneumonia with a new antibiotic adjuvant entity (ceftriaxone+sulbactam+disodium edetate) - A novel approach to spare carbapenems.
Ventilator associated pneumonia (VAP) is one of the most serious nosocomial infections in Intensive Care Unit (ICU). The aim of this study was to evaluate a new approach to spare the carbapenems for the management of patients diagnosed with VAP due to Acinetobacter baumannii (A. baumannii). ⋯ Clinical assessment with microbial eradication and pharmaco-economic evaluation clearly shows benefits in using AAE empirically in the management of A. baumannii infected VAP cases.
-
Journal of critical care · Oct 2017
Observational StudyThe impact of delayed rapid response call activation on patient outcomes.
To investigate the impact of delay in rapid response call (RRC) activation on Hospital mortality. ⋯ A delay of ≥15min was associated with significantly increased in-hospital mortality and longer hospitalization. The factors contributing to the observed increase in mortality with delayed RRCs require further exploration.
-
Journal of critical care · Oct 2017
U.S. drug shortages for medications used in adult critical care (2001-2016).
We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016. ⋯ Although the number of new shortages peaked in 2011 and is now declining, there remain a substantial number of active shortages impacting critical care drugs.