Journal of critical care
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Journal of critical care · Feb 2018
Multicenter StudyUntreated hypertension as predictor of in-hospital mortality in intracerebral hemorrhage: A multi-center study.
Hypertension is a significant risk factor for intracerebral hemorrhage (ICH). The importance of managing blood pressure to reduce the risk of ICH has been recognized. However, few studies have focused on ICH outcomes due to untreated hypertension. ⋯ Subjects with untreated-hypertension were younger and had fewer comorbidities when compared with treated-hypertension and were similar when compared to normotensive individuals. Once demographic and in-hospital factors were accounted for, untreated-hypertension subjects demonstrated significantly increased in-hospital mortality following ICH when compared with normotensive individuals.
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Journal of critical care · Feb 2018
Multicenter Study Observational StudyAssociation between strained capacity and mortality among patients admitted to intensive care: A path-analysis modeling strategy.
To evaluate the associations between strained ICU capacity and patient outcomes. ⋯ Strained capacity was associated with increased ICU mortality, partly mediated through greater illness acuity. Future work should consider both the direct and indirect relationships of strain on outcomes.
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Journal of critical care · Feb 2018
Revisiting the prognostic value of monocyte chemotactic protein 1 and interleukin-6 in the sepsis-3 era.
Monocyte Chemotactic Protein 1 (MCP1) and latest sepsis-3 criteria are poorly represented within studies evaluating biomarkers in sepsis. Therefore, this study evaluates the prognostic value of MCP-1 compared to interleukin-6 (IL-6) in patients with sepsis and septic shock according to sepsis-3 criteria. ⋯ Both MCP-1 and IL-6 revealed prognostic value for short- and mid-term all-cause mortality in patients with sepsis and septic shock according to latest sepsis-3 definitions.
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Journal of critical care · Feb 2018
ReviewEbola virus disease: Report from the task force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine.
Ebola virus is a filovirus that can cause fatal hemorrhagic fever (HF) and five distinct species exist that vary in terms of geographical distribution and virulence. Once the more virulent forms enter the human population, transmission occurs primarily through direct contact with infected body fluids and may result in significant outbreaks. The devastating has been the recent West African outbreak. ⋯ Real time reverse transcription-PCR (RT-PCR) techniques on blood specimens are the gold standard for diagnosis [6]. Management is discussed and is essentially supportive with strict attention to infection control and prevention. None of the pharmacological interventions have shown conclusive benefit and future management of epidemics should centre around prevention and containment, specifically isolation, hygiene, and vaccination.
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Journal of critical care · Feb 2018
Comparative StudyThe role of propionic acid at diagnosis predicts mortality in patients with septic shock.
This study aims to assess the diagnostic and prognostic value of propionic acid in patients with septic shock on a medical intensive care unit (ICU). ⋯ Propionic acid showed diagnostic capacity to diagnose septic shock and revealed prognostic information for mortality.