Journal of critical care
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Journal of critical care · Apr 2018
Randomized Controlled TrialAntioxidant reserve of the lungs and ventilator-associated pneumonia: A clinical trial of high dose selenium in critically ill patients.
To evaluate the effect of supplemental selenium administration on the incidence of ventilator-associated pneumonia (VAP) in critically ill patients. ⋯ Despite increasing the antioxidant activity, selenium supplementation did not affect the incidence of VAP in critically ill patients. The risk of developing VAP or death within 30days of ICU admission remained the same in the treatment and the controls.
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Journal of critical care · Apr 2018
Comparison of the performance of SOFA, qSOFA and SIRS for predicting mortality and organ failure among sepsis patients admitted to the intensive care unit in a middle-income country.
The Sepsis-3 definition provides a change of two or more scores from zero or a known baseline of the Sequential Organ Failure Assessment (SOFA) as criteria of sepsis. The aim of this study was to compare the SOFA score and the quick SOFA (qSOFA) to Systemic Inflammatory Response Syndrome (SIRS) criteria in predictive ability of mortality and organ failure. ⋯ The SOFA is a superior prognostic tool for predicting mortality and organ failure than qSOFA and SIRS criteria among sepsis patients admitted to the ICU.
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Journal of critical care · Apr 2018
End-organ recovery post-ventricular assist device can prognosticate survival.
This study examines our institutional ventricular assist devices (VADs) experience over two decades to understand trends towards predictors of mortality. ⋯ Persistent end-organ impairment in the first 2weeks after VAD placement could be a useful prognostic marker for survival to transplant.
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Journal of critical care · Apr 2018
Patient characteristics, incidence, technique, outcomes and early prediction of tracheostomy in the state of Victoria, Australia.
Tracheostomy is a relatively common procedure in Intensive Care Unit (ICU) patients. ⋯ The incidence of tracheostomy and the adjusted mortality rate of patients who received a tracheostomy have significantly decreased over a decade. Day of admission information could not be used to predict subsequent tracheostomy.
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Journal of critical care · Apr 2018
Review Meta AnalysisGenetic variants and acute kidney injury: A review of the literature.
Limited data exists on potential genetic contributors to acute kidney injury. This review examines current knowledge of AKI genomics. ⋯ Most studies of AKI genetics involve hypothesis-driven (rather than hypothesis-generating) candidate gene investigations that have failed to identify contributory variants consistently. A limited number of unbiased, larger-scale studies have been carried out, but there remains a pressing need for additional GWA studies.