Journal of critical care
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Journal of critical care · Apr 2018
End-organ recovery post-ventricular assist device can prognosticate survival.
This study examines our institutional ventricular assist devices (VADs) experience over two decades to understand trends towards predictors of mortality. ⋯ Persistent end-organ impairment in the first 2weeks after VAD placement could be a useful prognostic marker for survival to transplant.
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Journal of critical care · Apr 2018
Observational StudyPredictive factors for the outcome of high flow nasal cannula therapy in a pediatric intensive care unit: Is the SpO2/FiO2 ratio useful?
To determine the predictive factors for the outcome of high-flow nasal cannula (HFNC) therapy in a pediatric intensive care unit (PICU). ⋯ Monitoring the S/F ratio might be useful and practical to avoid delaying escalation to another ventilation support. Failure to achieve S/F>200 at 60min should be a warning for the escalation of respiratory support.
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Journal of critical care · Apr 2018
Review Meta AnalysisGenetic variants and acute kidney injury: A review of the literature.
Limited data exists on potential genetic contributors to acute kidney injury. This review examines current knowledge of AKI genomics. ⋯ Most studies of AKI genetics involve hypothesis-driven (rather than hypothesis-generating) candidate gene investigations that have failed to identify contributory variants consistently. A limited number of unbiased, larger-scale studies have been carried out, but there remains a pressing need for additional GWA studies.
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Journal of critical care · Apr 2018
Multicenter StudyMeasurement of respiratory rate by multiple raters in a clinical setting is unreliable: A cross-sectional simulation study.
To evaluate the inter-observer reliability of nurses assessing respiratory rate. ⋯ We found a wide variation in measurements of RR with both few and many observers assessing exactly the same patients.