Journal of critical care
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Journal of critical care · Jun 2018
Sustained increase in angiopoietin-2, heparin-binding protein, and procalcitonin is associated with severe sepsis.
The identification of infection at its early stage in vulnerable patients is challenging. This study aimed to investigate potential biomarkers to distinguish patients progressing to severe sepsis from those with uncomplicated sepsis. ⋯ These findings indicated that sustained elevation of Ang-2, HBP, and PCT were associated with severe infection in critically ill patients.
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Journal of critical care · Jun 2018
Dead space analysis at different levels of positive end-expiratory pressure in acute respiratory distress syndrome patients.
To analyze the effects of positive end-expiratory pressure (PEEP) on Bohr's dead space (VDBohr/VT) in patients with acute respiratory distress syndrome (ARDS). ⋯ Increases in PEEP result in higher VDBohr/VT only when associated with an increase in driving pressure.
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Journal of critical care · Jun 2018
ReviewThe critically ill patient with tuberculosis in intensive care: Clinical presentations, management and infection control.
Tuberculosis (TB) is one of the top ten causes of death worldwide. In 2016, there were 490,000 cases of multi-drug resistant TB globally. Over 2 billion people have asymptomatic latent Mycobacterium tuberculosis infection. ⋯ The mortality of patients requiring intensive care is high. The majority of early TB deaths result from acute cardiorespiratory failure or septic shock. Important clinical presentations, management and infection control issues regarding TB in intensive care settings are reviewed.
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Journal of critical care · Jun 2018
Observational StudySuccessful weaning from continuous renal replacement therapy. Associated risk factors.
To identify risk factors of successful continuous renal replacement therapy (CRRT) weaning and to evaluate the effect of furosemide in the recovery of urine output after CRRT stop. ⋯ Urine output after CRRT stop was the main risk factor of successful CRRT weaning. Administration of furosemide increased the strength of this association.
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Journal of critical care · Jun 2018
Early nutritional inadequacy is associated with psoas muscle deterioration and worse clinical outcomes in critically ill surgical patients.
To explore whether psoas cross sectional area (CSA) and density (Hounsfield Units, HU) are associated with nutritional adequacy and clinical outcomes in surgical intensive care unit patients. ⋯ In this exploratory study, early nutritional deficits were correlated with muscle quality deterioration. Inpatient gain in psoas density, compared to maintenance or loss, is associated with shorter hospital stay.