Journal of critical care
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Journal of critical care · Dec 2020
Observational StudyInadequate prophylactic effect of low-molecular weight heparin in critically ill COVID-19 patients.
The aim of this study was to investigate potential markers of coagulopathy and the effects of thromboprophylaxis with low-molecular-weight heparin (LMWH) on thromboelastography (TEG) and anti-factor Xa in critically ill COVID-19 patients. ⋯ Patients with COVID-19 have hypercoagulability with high MA on TEG. The effect of LMWH on thromboembolic disease, anti-factor Xa activity and TEG was variable and could not be reliably predicted. This indicates that standard prophylactic doses of LMWH may be insufficient. Monitoring coagulation and the LMWH effect is important in patients with COVID-19 but interpreting the results in relation to risk of thromboembolic disease poses difficulties.
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Journal of critical care · Dec 2020
Observational StudyEpidemiology and outcomes of acute kidney injury in cardiac intensive care unit patients.
To describe the epidemiology and outcomes of acute kidney injury (AKI) among contemporary non-surgical cardiac intensive care unit (CICU) patients. ⋯ AKI severity is incrementally associated with higher short-term and long-term mortality in CICU patients, especially severe AKI requiring dialysis.
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Journal of critical care · Dec 2020
The wave of very old people in the intensive care unit-A challenge in decision-making.
In this paper the authors express the opinion that there is much to be learned about the 80+ year old age group as it relates to critical care and end-of-life matters. We need to learn how to better predict outcome, we need to learn our limitations and deal with uncertainties, we need to better communicate with our elderly patients and their caregivers and we need to engage with our colleagues in Geriatrics. There is a wave of very old people arriving in the intensive care unit and we have much to do to prepare for it and for the ethical, fair and appropriate care of these critically ill, but elderly, patients.
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Journal of critical care · Dec 2020
Do perceived honorary authors influence publication chance? Survey evidence from the journal of critical care.
Perceived Honorary Authors (PHAs) are defined as authors on manuscripts who did not contribute enough. The association between PHAs and publication chance in journals is unknown. As a start, our aim was to examine the prevalence of PHAs in the Journal of Critical Care (JCC). Furthermore, we investigated whether PHAs influences publication chance in the JCC. Also, we attempt to replicate factors associated with the prevalence of PHAs found in earlier studies. ⋯ The prevalence of PHAs was conform other studies 13%, and did not influence publication chance.
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Journal of critical care · Dec 2020
Supervised machine learning for the early prediction of acute respiratory distress syndrome (ARDS).
Acute respiratory distress syndrome (ARDS) is a serious respiratory condition with high mortality and associated morbidity. The objective of this study is to develop and evaluate a novel application of gradient boosted tree models trained on patient health record data for the early prediction of ARDS. ⋯ Supervised machine learning predictions may help predict patients with ARDS up to 48 h prior to onset.