Journal of critical care
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Journal of critical care · Dec 2018
Meta AnalysisPrognostic value of plasma brain natriuretic peptide value for patientswith sepsis: A meta-analysis.
The aim of this meta-analysis was to clarify the diagnostic role of plasma BNP and NT-proBNP in predicting mortality for septic patients. ⋯ This meta-analysis indicates that both elevated plasma BNP and NT-proBNP have moderate predicts value for the mortality of septic patients, and the tested method and observation endpoint influence the results of BNP.
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Journal of critical care · Oct 2018
Review Meta AnalysisAssociation between arterial hyperoxia and mortality in critically ill patients: A systematic review and meta-analysis.
The relationship between arterial hyperoxia exposure and clinical outcome is under increasing scrutiny. We therefore performed an update meta-analysis to evaluate the effect of arterial hyperoxia on hospital mortality in critically ill adults. ⋯ The results of current meta-analysis suggest that arterial hyperoxia may be associated with increased hospital mortality in critically ill patients.
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Journal of critical care · Oct 2018
Meta AnalysisNon-invasive ventilation in children and adults in low- and low-middle income countries: A systematic review and meta-analysis.
We systematically reviewed the effects of NIV for acute respiratory failure (ARF) in low- and low-middle income countries. ⋯ NIV for ARF in these settings appears to be effective.
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Journal of critical care · Jun 2018
Review Meta AnalysisReduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis.
B cell function and antibody production are crucial factors in host protection during inflammation. We aimed to synthesize the available evidence on the association between the reduction of circulating B cells and plasma immunoglobulin (IgM) levels and decreased survival during sepsis. ⋯ The protocol was registered (PROSPERO 2016:CRD42016053184).
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Journal of critical care · Apr 2018
Review Meta AnalysisGenetic variants and acute kidney injury: A review of the literature.
Limited data exists on potential genetic contributors to acute kidney injury. This review examines current knowledge of AKI genomics. ⋯ Most studies of AKI genetics involve hypothesis-driven (rather than hypothesis-generating) candidate gene investigations that have failed to identify contributory variants consistently. A limited number of unbiased, larger-scale studies have been carried out, but there remains a pressing need for additional GWA studies.