Journal of critical care
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Journal of critical care · Apr 2020
Muscle wasting associated co-morbidities, rather than sarcopenia are risk factors for hospital mortality in critical illness.
Low skeletal muscle mass on intensive care unit admission is related to increased mortality. It is however unknown whether this association is influenced by co-morbidities that are associated with skeletal muscle loss. The aim of this study was to investigate whether sarcopenia is an independent risk factor for hospital mortality in critical illness in the presence of co-morbidities associated with muscle wasting. ⋯ In critically ill patients with abdominal sepsis, muscle wasting associated co-morbidities rather than sarcopenia were risk factors for hospital mortality.
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Journal of critical care · Apr 2020
Impact of obstructive sleep apnea on the obesity paradox in critically ill patients.
Patients admitted to an intensive care unit (ICU) frequently suffer from multiple chronic diseases, including obstructive sleep apnea (OSA). Until recently OSA was not considered as a key determinant in an ICU patient's prognosis. The objective of this study was to document the impact of OSA on the prognosis of ICU patients. ⋯ In general, known OSA did not increase the ICU stay except for patients with both OSA and morbid obesity.
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Journal of critical care · Apr 2020
Observational StudyCharacteristics and outcomes of critically ill patients with severe hyperammonemia.
To determine the etiology and outcomes of critically ill patients with severe hyperammonemia. ⋯ Critically ill patients with severe hyperammonemia have a high mortality rate and are at risk of developing cerebral edema.
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Journal of critical care · Apr 2020
Observational StudyMuscle degradation, vitamin D and systemic inflammation in hospitalized septic patients.
To date, the relationship between systemic inflammation and muscle changes observed by ultrasonography in septic patients in clinical studies is not known. Furthermore, the role of vitamin D on muscle changes in these patients needs to be investigated. ⋯ In septic patients, there is an association between inflammation and changes in muscle mass and strength during ICU stay, which is similar to those observed in experimental studies. In addition, there was an association of vitamin D with recovery of muscle strength during hospitalization.
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Journal of critical care · Apr 2020
Observational StudyEffects of intraoperative tidal volume on incidence of acute kidney injury after cardiovascular surgery: A retrospective cohort study.
We performed a retrospective cohort study to evaluate whether intraoperative low tidal volume ventilation reduces the incidence of acute kidney injury (AKI) after cardiovascular surgery. ⋯ This study suggests that intraoperative low tidal volume ventilation during cardiovascular surgery is associated with a decreased incidence of postoperative AKI. Lowering tidal volume might be a simple strategy for reducing AKI incidence after cardiovascular surgery.