Journal of critical care
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Journal of critical care · Feb 2020
Gas exchange, specific lung elastance and mechanical power in the early and persistent ARDS.
Aim of this study was to evaluate the effect of acute respiratory distress syndrome (ARDS) duration on gas-exchange, respiratory mechanics, specific lung elastance and mechanical power. ⋯ The persistent phase of ARDS for 7-days did not affect the respiratory mechanics while significantly impaired the PaCO2 exchange.
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Journal of critical care · Feb 2020
The influence of clinical variables on the risk of developing chronic conditions in ICU survivors.
To assess the association of clinical variables and the development of specified chronic conditions in ICU survivors. ⋯ Clinical variables, especially the reason for ICU admission, are associated with the development of chronic conditions after ICU discharge. Therefore, these clinical variables should be considered when organizing follow-up care for ICU survivors.
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Journal of critical care · Feb 2020
Population pharmacokinetic model of Vancomycin based on therapeutic drug monitoring data in critically ill septic patients.
The present study aimed to establish a population pharmacokinetic model of vancomycin, including adult critically ill septic patients, with normal and impaired renal function. ⋯ The developed population vancomycin model may be used in estimating individual CL for adult critically ill septic patients, and could be applied for individualizing dosage regimens taking into account the continuous effect of CrCl.
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Journal of critical care · Feb 2020
The Japanese Intensive care PAtient Database (JIPAD): A national intensive care unit registry in Japan.
The Japanese Intensive care PAtient Database (JIPAD) was established to construct a high-quality Japanese intensive care unit (ICU) database. ⋯ The data revealed that the SMRs based on general severity scores in adults were low because of high proportions of elective and monitoring admission. The development of a new mortality prediction model for Japanese ICU patients is needed.