Journal of critical care
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Goal of this study was to describe incidence and outcome of gastrointestinal failure (GIF) in ICU patients, evaluate its additive role to SOFA score in mortality prediction and describe GIF according to etiology. ⋯ Gastrointestinal failure, independent of origin, is associated with worse ICU outcome. Similar to other organ failures included in SOFA score, GIF independently predicts mortality.
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Journal of critical care · Aug 2019
Observational StudyThe effect of emergency department crowding on lung-protective ventilation utilization for critically ill patients.
To measure effects of ED crowding on lung-protective ventilation (LPV) utilization in critically ill ED patients. ⋯ ED patients remain on suboptimal tidal volume settings with infrequent ventilator adjustments during the ED stay. Hospitals should focus on both systemic factors and bedside physician and/or respiratory therapist interventions to increase LPV utilization in times of ED boarding and crowding for all patients.
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Journal of critical care · Aug 2019
Kinetic analysis of cardiac compressions during cardiopulmonary resuscitation.
Little is known about the dynamics of cardiac compression during cardiopulmonary resuscitation (CPR). The purpose of this study was to investigate the dynamics of chest compressions by analyzing movement of the right ventricular free wall excursion during CPR. ⋯ Maintaining high compression velocity is helpful in achieving adequate compression depth during CPR.
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Journal of critical care · Aug 2019
Comparative Study Observational StudyEvaluation of MR-proANP and copeptin for sepsis diagnosis after burn injury.
The significance of the validated biomarkers of sepsis Mid-regional pro-atrial natriuretic peptide (MR-proANP) and copeptin have not been tested in a burn injury setting. ⋯ Burn injury itself maybe associated with copeptin and to a lesser degree MR-proANP level increases. Subsequent increases in MR-proANP may be considered diagnostic for sepsis but demonstrated no advantages over PCT. The role of copeptin remains inappropriate for diagnosing sepsis after burn injury (ClinicalTrials.gov number, NCT01055587).
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Journal of critical care · Aug 2019
Comparative Study Observational StudyAnti-Xa activity by weight in critically ill patients receiving unfractionated heparin for venous thromboembolism prophylaxis.
This study compared anti-Xa activity in critically ill patients receiving UFH for VTE prophylaxis between two weight groups (<100 kg vs ≥100 kg). ⋯ Though only one-third of patients ≥100 kg had peak anti-Xa activity within goal range, no significant difference was found between the weight groups. Additional prospective studies with adequate sample sizes are warranted to further investigate appropriate weight-based dosing of UFH in critically ill patients.