Journal of critical care
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Journal of critical care · Apr 2018
Magnesium supplementation: Pharmacokinetics in cardiac surgery patients with normal renal function.
Intravenous magnesium is routinely administered in intensive care units (ICU) to treat arrhythmias after cardiothoracic surgery. There are no data on the pharmacokinetics of continuous magnesium infusion therapy. ⋯ Combined bolus and continuous magnesium infusion therapy leads to a significant and stable increase in magnesium serum concentration despite increased renal excretion and redistribution.
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Journal of critical care · Apr 2018
Effect of various antipsychotic regimens on incidence of delirium in critically ill adults.
Delirium is common during critical illness but it is unknown whether the choice of antipsychotic or dosing strategy impacts delirium outcomes. We evaluated the incidence of delirium in critically ill adults receiving different antipsychotic regimens. ⋯ There was no difference in incidence or duration of delirium between quetiapine and haloperidol regimens.