Journal of critical care
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Journal of critical care · Jun 2014
Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients.
This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. ⋯ Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.
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Journal of critical care · Jun 2014
The potential efficacy of noninvasive ventilation with administration of a neutrophil elastase inhibitor for acute respiratory distress syndrome.
Noninvasive ventilation (NIV) can reduce the need for invasive mechanical ventilation. The aim of this investigation was to determine whether the combination of NIV with administration of a neutrophil elastase inhibitor could improve outcome and respiratory conditions in acute respiratory distress syndrome (ARDS)-patients, according to the Berlin definition. ⋯ Administration of neutrophil elastase inhibitor with NIV may be associated with successful outcome in mild-to-moderate ARDS-patients with initial PaO2/FiO2>150.
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Journal of critical care · Jun 2014
Observational StudyEvaluation of a dosing regimen for continuous vancomycin infusion in critically ill patients: An observational study in intensive care unit patients.
We aimed to evaluate a dosing algorithm for continuous vancomycin administration in intensive care unit patients. ⋯ The evaluated vancomycin dosing regimen for continuous infusion allowed rapid achievement of sufficient vancomycin serum levels. However, we frequently observed supra-therapeutic serum vancomycin concentrations in the first days of vancomycin treatment.