The International journal of oral & maxillofacial implants
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Int J Oral Maxillofac Implants · Jan 2009
The effects of recombinant human growth/differentiation factor-5 (rhGDF-5) on bone regeneration around titanium dental implants in barrier membrane-protected defects: a pilot study in the mandible of beagle dogs.
This dog study sought to evaluate guided bone regeneration (GBR) in peri-implant defects following implantation of beta-tricalcium phosphate (beta-TCP) with and without osteoinductive recombinant human growth/differentiation factor-5 (rhGDF-5). ⋯ Delivery of rhGDF-5 on beta-TCP might have the potential to enhance the results of GBR in peri-implant defects.