Pediatric hematology and oncology
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Pediatr Hematol Oncol · Sep 2003
Case ReportsEncouraging result of tamoxifen in a retinoblastoma patient with central nervous system metastasis.
Extraocular retinoblastoma occurs more frequently in developing countries as a delayed diagnosis and prognosis of patients with conventional therapy is very poor. Metastatic retinoblastoma, especially in the central nervous system (CNS), is a highly lethal disease. ⋯ She was in remission until she has died in a traffic accident at week 114. The authors think that tamoxifen can be added to treatment protocols of metastatic retinoblastoma to provide longer and at least higher quality of life for these patients.