Archivos de bronconeumología
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Varicella is a self-limited, benign disease in childhood. When it affects adults, however, serious complications can develop, the most frequent and most dangerous being pneumonia. Adults who develop varicella should be followed closely, with careful attention given to respiratory symptoms in particular, from the first week the rash is evident until it begins to fade. Should pneumonia appear, early start of intravenous acyclovir therapy is indicated in immunodepressed or pregnant patients, or in immunocompetent patients with respiratory problems.
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Arch. Bronconeumol. · Aug 1996
[Hypercapnic stimulation and ventilation response in the syndrome of sleep obstructive apnea. Comparison of reinhalation and steady state].
The objective of this study was to assess ventilatory response to stimulation with CO2 in patients suffering obstructive sleep apnea syndrome (OSAS) but without chronic obstructive pulmonary disease (COPD), by examining differences between hyper- and normocapnic patients and comparing the results obtained with the usual techniques used to stimulate hypercapnia (rebreathing and stable-state). To this end, we studied 15 obese patients, all with an apnea-hypopnea index greater than 10 from a polysomnograph lasting a full night. The following lung function tests were performed: spirometry, air way resistance measures and static lung volumes by plethysmograph and arterial gasometry. ⋯ The results from the two techniques for stimulating hypercapnia were similar within each group, with a statistically significant decrease (p < 0.03) in patients with daytime hypercapnia in delta VE/delta PCO2 delta Vt/delta PCO2, delta Vt/Ti/delta PCO2 and delta P0.1/delta PCO2. We conclude that there are no differences in the results obtained with the rebreathing and stable state techniques. Likewise, ventilatory response to stimulation with CO2 in individuals with OSAS and daytime hypoventilation is less than of normocapnic patients.