Archivos de bronconeumología
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Arch. Bronconeumol. · Sep 2018
Hypercapnia Response in Patients with Obesity-Hypoventilation Syndrome Treated with Non-Invasive Ventilation at Home.
Respiratory center (RC) dysfunction has been implicated in the pathogenesis of obesity-hypoventilation syndrome (OHS), and often requires treatment with home non-invasive ventilation (NIV). Our objective was to measure the effect of NIV on RC function in patients with OHS, and the factors that determine such an effect. ⋯ In total, 63% of OHS patients had RC dysfunction. The application of NIV improves RC function but not in all cases.