Archivos de bronconeumología
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Arch. Bronconeumol. · Feb 2019
Multicenter Study Observational StudyPrognostic Value of Frequent Exacerbations in Bronchiectasis: The Relationship With Disease Severity.
Bronchiectasis is a very heterogeneous disease but some homogeneous groups with similar clinical characteristics and prognosis have been identified. Exacerbations have been shown to have a negative impact on the natural history of bronchiectasis. The objective of this study was to identify the definition and characteristics of the "frequent exacerbator patient" with the best prognostic value and its relationship with the severity of bronchiectasis. ⋯ The combination of two exacerbations or one hospitalization per year is the definition of frequent exacerbator patient that has the best predictive value of mortality independent of the initial severity of bronchiectasis.