Human reproduction
-
Randomized Controlled Trial Comparative Study Clinical Trial
A randomized controlled trial comparing medical and expectant management of first trimester miscarriage.
We aimed to determine whether outpatient treatment of miscarriage with vaginal misoprostol is more effective than expectant management in reducing the need for surgical evacuation of retained products of conception (ERPC). ⋯ Medical management using 600 microg misoprostol vaginally is more effective than expectant management of early pregnancy failure. Misoprostol did not increase the side-effect profile and patient acceptability was superior to expectant management.