Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
To describe the influence of sevoflurane anesthesia on cisatracurium neuromuscular block in a myasthenic patient undergoing thymectomy. ⋯ The marked sensitivity of this myasthenic patient to 0.5 x ED95 of cisatracurium can be attributed to potentiation of cisatracurium neuromuscular block by sevoflurane, as evidenced by the reappearance of the first twitch of the train-of-four response 10 min after sevoflurane was discontinued.
-
Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Postoperative pain management in patients undergoing major surgery after remifentanil vs. fentanyl anesthesia. Multicentre Investigator Group.
To determine if morphine sulphate was an effective transition analgesic in patients receiving a remifentanil-based anesthetic regimen. ⋯ Morphine sulphate regimens of 0.15 or 0.20 mg x kg(-1) administered 30 min before the end of surgery are equally effective transition regimens for inpatient procedures.
-
To estimate the efficacy and harm produced by droperidol in the prevention of postoperative nausea and vomiting (PONV). ⋯ Droperidol is anti-emetic in the surgical setting. The effect on nausea is short-lived but more pronounced than the effect on vomiting. Sedation and drowsiness are dose-dependent, extrapyramidal symptoms are rare, and there is a protective effect against headache.
-
To review the clinical benefits of dextromethorphan (DM) in pain management, describe its neuropharmacological properties. ⋯ DM attenuates acute pain sensation with tolerable side effects. Its availability in oral form bestow advantages over other NMDA antagonists.
-
To compare the spinal-epidural spread of gas following loss of resistance (LOR) technique for detection of the epidural space using air or nitrous oxide (N2O). ⋯ The use of N2O for LOR technique of detecting the epidural space produced very small bubbles detected by MRI compared with the use of air under similar conditions.