Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Comparative Study Clinical Trial
The Microcuff tube allows a longer time interval until unsafe cuff pressures are reached in children.
To compare cuff pressures during nitrous oxide exposure in the new Microcuff pediatric tracheal tube (MPT) with ultrathin high volume - low pressure polyurethane cuff to a tube with a standard polyvinyl chloride (PVC) cuff. ⋯ When baseline inflation pressure was set at 20 cm H(2)O, cuff pressure increased similarly in MPT and PVC tubes. When inflated just to sealing pressure, the MPT allowed a longer time interval until the upper limit of 25 cm H(2)O was reached.
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Randomized Controlled Trial Clinical Trial
Preemptive gabapentin decreases postoperative pain after lumbar discoidectomy.
We investigated whether the preemptive use of gabapentin, a structural analogue of gamma amino butyric acid could reduce postoperative pain and fentanyl consumption in patients after single-level lumbar discoidectomy. ⋯ Preemptive gabapentin 300 mg po significantly decreases the severity of pain postoperatively in patients who undergo single-level lumbar discoidectomy.
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Randomized Controlled Trial Clinical Trial
Aprotinin decreases the incidence of cognitive deficit following CABG and cardiopulmonary bypass: a pilot randomized controlled study.
Cognitive deficit after coronary artery bypass surgery (CABG) has a high prevalence and is persistent. Meta-analysis of clinical trials demonstrates a decreased incidence of stroke after CABG when aprotinin is administrated perioperatively. We hypothesized that aprotinin administration would decrease the incidence of cognitive deficit after CABG. ⋯ In this prospective pilot study, the incidence of cognitive deficit after CABG and cardiopulmonary bypass is decreased by the administration of high-dose aprotinin.