Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
To provide evidence-based guidelines for the prophylaxis and treatment of postoperative nausea and vomiting (PONV). ⋯ PONV are common after anesthesia and surgery. We provided evidence-based guidelines for the management of this problem based on the available literature.
-
Review
Massive transfusion and coagulopathy: pathophysiology and implications for clinical management.
To review the pathophysiology of coagulopathy in massively transfused, adult and previously hemostatically competent patients in both elective surgical and trauma settings, and to recommend the most appropriate treatment strategies. ⋯ Coagulopathy associated with massive transfusion remains an important clinical problem. It is an intricate, multifactorial and multicellular event. Treatment strategies include the maintenance of adequate tissue perfusion, the correction of hypothermia and anemia, and the use of hemostatic blood products to correct microvascular bleeding.